I had a strange episode the other night.
I woke up and thought I had had a stroke. My legs were like jelly, my arms had no strength, and movement was very slow motion. My brain was functioning quite well, although I had no volume to my speech.
I contemplated ringing the ambulance, but decided to stay calm , breathe deeply and do all the tests the doctors would do to diagnose a stroke. I took an asprin, and lay there slowly trying to regain control. It took 30 minutes, and slowly my strength came back. Was it a panick attack, was it a mini stroke, was it something weird? The CT scan the following morning came back clear, except for a diagnosis of, "normal scan. idiopathic calcification of the basal ganglia.'

Normal, it stated clearly. In fact, it was so normal that my doctor didn't even look at the result, until I brought it up. But when I asked her opinion about it, she didn't have a clue what it was. I have been feeling dizzy, slightly off balance, have aching muscles for 2 years, occasional facial neuropathy, headaches, and strange depression, which I never realy had. I am 52, but the doctors cannot work it out. I should be healthy.

This page will attempt to provide information about this 'rare disease", as I gather data from as many places as possible. It may not be the cause of my present symptoms, but so far in my research, it appears that it will undoubtedly have some effects at one point in my life. If anyone has any information, please add it to the page. Please click on my post headlines to take you direct to the relevant sites.Cheers.

Thursday, April 29, 2010

American Society of Microbiology article

This article from the american society of Microbiology is very in depth, and covers research into the Human herpesvirus 6 (HHV-6). The research suggest the possibility of HHV- being a co contributor to MS and other brain diseases. Please read the full citation for an overview.

The high fever, characteristic of HHV-6 primary infection, is often accompanied by seizures, and HHV-6 reactivation in immunocompromised patients is associated with severe encephalitis and/or encephalopathy. There have been case reports on immunocompetent and immunocompromised adults with severe CNS disease due to HHV-6 active infection, which was characterized by a fulminant multifocal demyelinating disease (32, 115, 262, 313, 329, 410). The neuroinvasiveness of the virus is proven by the fact that HHV-6 DNA is frequently detected in specimens from divergent regions of the brain (incidence rate of individuals with positive HHV-6 PCR on brain tissue, 32 to 85%) (60, 61, 83, 110, 249). Both A and B variants of HHV-6 have been found in a proportion reflecting their seroprevalence (the B variant being approximately three times more frequent than the A variant). Some patients harbor both variants, though at different locations within the brain (60). However, in a large prospective study including 2,716 children with acute ES, either HHV-6A or HHV-6B DNA, but not both, was detected in the CSF during the active phase (153). In patients with dual infection, only HHV-6A persisted in CSF, which may suggest that HHV-6A has greater neurotropism. Altogether, these studies prove that the brain is an important site for active and latent HHV-6 infection
( Clinical Microbiology Reviews, January 2005, p. 217-245, Vol. 18, No. 1 MORE


0893-8512/05/$08.00+0 doi:10.1128/CMR.18.1.217-245.2005

Copyright © 2005, American Society for Microbiology. All Rights Reserved.)

1 comment:

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